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Umntwana ulala phantsi kwe-ainethi yeengcongconi.Kuphononongo lwakutsha nje, iminatha enyangwa nge-clofenapyr inciphise ukuxhaphaka kwemalariya ngama-43% kunyaka wokuqala kunye ne-37% kunyaka wesibini xa kuthelekiswa nenethi eqhelekileyo ye-pyrethroid-only.Photos |Amaxwebhu
Uhlobo olutsha lomnatha webhedi olunokuthi luthintele iingcongconi ezikwaziyo ukumelana nezitshabalalisi zemveli lunciphise kakhulu usulelo lwemalariya eTanzania, izazinzulu zithi.
Xa kuthelekiswa neminatha eqhelekileyo ye-pyrethroid-only, inetha yanciphisa kakhulu ukuxhaphaka kwemalariya, yanciphisa amazinga osulelo lwabantwana phantse ngesiqingatha kwaye yanciphisa iziqephu zekliniki zesi sifo ngama-44 ekhulwini kwiminyaka emibini yolingo lwaso.
Ngokungafaniyo namayeza okubulala izinambuzane abulala iingcongconi, iminatha emitsha yenza ukuba iingcongconi zingakwazi ukuzinyamekela, ukushukuma okanye ukuluma, zibulawa yindlala, ngokophando olupapashwe ngoMatshi kwiLancet.
Kolu phononongo olubandakanya amakhaya angaphezu kwama-39,000 kunye nabantwana abangaphezu kwe-4,500 eTanzania, kwafunyaniswa ukuba inethi ezibulala izinambuzane ezihlala ixesha elide ziphathwa ngezinambuzane ezimbini, i-chlorfenapyr kunye ne-chlorfenapyr LLIN, ukunciphisa ukuxhaphaka kweMalariya kwancitshiswa ngama-43% xa kuthelekiswa neminatha ye-pyrethroid kuphela. , kunye nokunciphisa okwesibini kwe-37%.
Uphononongo lwafumanisa ukuba i-clofenapyr ikwanciphisa inani leengcongconi ezinemalariya ezifunyenwe ngama-85 ekhulwini.
Ngokutsho kwezazinzulu, i-clofenapyr yenza ngokungafaniyo kune-pyrethroids ngokubangela i-spasms kwimisipha ye-pterygoid, ethintela umsebenzi wemisipha yendiza.Oku kuthintela ukuba iingcongconi zingadibanisi okanye zilume imikhosi yazo, ekugqibeleni inokukhokelela ekufeni kwabo.
UGqr. Manisha Kulkarni, unjingalwazi oncedisayo kwiYunivesithi yaseOttawa’s School of Epidemiology, wathi: “Umsebenzi wethu wokongeza i-clofenac kwiminatha eqhelekileyo yepyrethroid unamandla amakhulu okulawula isifo seengcongconi esisasazwa ziingcongconi ezingevayo ngamayeza eAfrika ‘ngokucofa’ iingcongconi.“Impilo yoluntu.
Ngokuchaseneyo, inethi zokulala zinyangwa nge-pieronyl butoxide (PBO) ukunyusa ukusebenza kwe-pyrethroids yanciphisa usulelo lwemalariya ngama-27% phakathi kweenyanga ezili-12 zokuqala zolingo, kodwa emva kweminyaka emibini kusetyenziswa iinethi eziqhelekileyo.
Umnatha wesithathu ophathwe nge-pyrethroid kunye ne-pyriproxyfen (i-mosquitos zabasetyhini ezingenayo i-neutered) zinempembelelo encinci eyongezelelweyo xa kuthelekiswa neminatha ye-pyrethroid eqhelekileyo.
“Nangona kubiza kakhulu, ixabiso eliphezulu le-clofenazim LLIN liyathotywa kukongiwa kokunciphisa inani leemeko zemalariya ezifuna unyango.Ngoko ke, amakhaya kunye noluntu olusasaza iminatha ye-clofenazim kunokwenzeka ukuba iindleko zizonke zilindeleke ukuba zibe phantsi, "lathi iqela lezenzululwazi, elithemba ukuba i-World Health Organization kunye neenkqubo zokulawula isifo seengcongconi ziya kwamkela iminatha emitsha kwiindawo ezine-insecticide-resistant. iingcongconi.
Iziphumo ezivela kwiNational Institute of Medicine, iKilimanjaro Christian University College of Medicine, iLondon School of Hygiene kunye neTropical Medicine (LSHTM) kunye neYunivesithi yase-Ottawa ziindaba ezamkelekileyo kwilizwekazi apho iminatha yokulala esemgangathweni iyasilela ekukhuseleni abantu kwii-parasites.
Iinethi ezityatyiswe ngamayeza okubulala izinambuzane zincede ekuthinteleni i-68% yeemeko zemalariya kwi-Afrika ekwi-sub-Saharan Africa phakathi kuka-2000 no-2015. Kwiminyaka embalwa edlulileyo, nangona kunjalo, ukuhla kweqondo lemalariya kuye kwanqumama okanye kwade kwajika kwamanye amazwe.
Abantu abangama-627,000 babulawa sisifo seengcongconi ngo-2020, xa kuthelekiswa nama-409,000 ngo-2019, uninzi e-Afrika nasebantwaneni.
“Ezi ziphumo zivuyisayo zibonisa ukuba sinesinye isixhobo esisebenzayo sokunceda ukulawula isifo seengcongconi,” utshilo umbhali ophambili wolu phando, uGqr Jacklin Mosha ovela kwiZiko leSizwe loPhando lwezoNyango eTanzania.
I-"in-flying, non-in-biting mosquito networked net," ithengiswa njenge "Interceptor® G2," inokukhokelela ekuzuzeni okubonakalayo kokulawulwa kwe-malaria kwi-Afrika engaphantsi kwe-Sahara, iqela lathi.
Nangona kunjalo, bathi uphando olongezelelweyo luyafuneka ukuvavanya ukuba nokwenzeka kokunyusa kunye nokucebisa izicwangciso zokulawula ukuchasana ezifunekayo ukuze kugcinwe ukusebenza kwexesha elide.
Omnye umbhali uNatacha Protopopoff ulumkisa ngelithi: “Kufuneka silumke.” Ukwanda okukhulu kwe-LLIN eqhelekileyo kwiminyaka eli-10 ukuya kwengama-20 eyadlulayo kwakhokelela ekwandeni okukhawulezileyo kokuxhathisa kwepyrethroid.Umceli mngeni ngoku kukugcina ukusebenza kwe-clofenazepam ngokuphuhlisa izicwangciso zokulawula ukuxhathisa.
Esi sesokuqala kwiimvavanyo ezininzi ngenethi zeengcongconi ze-clofenapyr.Abanye baseBenin, eGhana, eBurkina Faso naseCôte d'Ivoire.
Imimandla eyinkqantosi nebharhileyo yayiyeyona ichaphazeleke kakhulu, imveliso yelizwe yehle ngama-70 ekhulwini.